chromosome arm

The chromosome arm is already copied during S phase of the cell cycle.

Only part of the duplicated region may have been transposed to the other chromosome arm.

These clusters could cover an entire chromosome arm.

Other frequent abnormalities include structural rearrangement of 1p, 3p, 9p and 6q chromosome arms.

To generate quality scores for an entire chromosome arm, we associated a phrap consensus score with each base.

Consistent with this is the fact that rearranged sequences can be inferred to come from the same chromosome arm.

We did not substantially extend the proximal sequence of chromosome arm 3R in Release 3.

The assembly of the individual BACs into entire chromosome arms was verified in two ways.

The remaining autosomal pairs are smaller and acrocentric (with the shorter chromosome arm difficult to observe).

The Release 3 chromosome arms are composed of 13 sequence scaffolds and contain 31 sequence gaps.

The proximal sequence of chromosome arm 2R is highly enriched in transposable element sequence.

The proximal sequence of chromosome arm 2L ends in 15 kb of nested transposable elements.

These data show that the large Release 3 sequence contigs extend into the centric heterochromatin on these five chromosome arms.

In addition, the differently stained regions and sub-regions are given numerical designations from proximal to distal on the chromosome arms.

The largest sequence contig covers the entire chromosome arm 3R in a single contig of 27 Mb.

This may reflect more complete sequencing on 1p, or perhaps differing DNA-packing densities on the two chromosome arms.

Second, the unique end sequences of 8,424 BACs were aligned to the assembled chromosome arm sequences.

The sequence of chromosome arm 4 in Release 3 extends proximally to that of Release 2 by nearly 60 kb.

We used the reannotated chromosome arm 2R [ 35] to evaluate our ability to predict promoter regions in a complete eukaryotic chromosome.

FRT sites have been inserted transgenically near the centromere of each chromosome arm of Drosophila melanogaster.

Cancer cells frequently have aneuploidy of chromosomes and chromosome arms, although a cause and effect relationship between aneuploidy and cancer has not been established.

Homologous chromosome arms in the genus Drosophila are referred to as Muller's elements, and represent a clearly established level of synteny between species [ 7].

Familial melanoma is genetically heterogeneous, and loci for familial melanoma have been identified on the chromosome arms 1p, 9p and 12q.

For example, of the 55 Drosophila genes that had a single clear homolog in Anopheles , 27 are located on D. melanogaster chromosome arm 2R.