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This result is most likely due to the considerably higher consistency of the chromosomal inversion data.
More striking still, researchers discovered a so-called chromosomal inversion.
The main objective of the present study is to place the chromosomal inversion data into a phylogenetic framework.
Results and Discussion Chromosomal inversions Table 1lists the sources of the data used in this study.
Chromosomal inversion data are much more information rich as assessed in the present study, and this is probably due to the higher consistency of these characters.
It can occur as a result of: translocation, interstitial deletion, or chromosomal inversion.
Chromosomal inversions: reversing the orientation of a chromosomal segment.
Conclusion Classical Drosophila studies have used chromosomal inversions to understand phylogeny and speciation.
Our results suggest that there is a great deal of congruence among DNA sequence data and chromosomal inversion data.
Chromosomal inversion, reordering of genes in a DNA-sequence.
Using Painter's technique they studied the polytene chromosomes and discovered that the wild populations were polymorphic for chromosomal inversions.
The rarest cause of BFNE, occurring in only one known family, is a chromosomal inversion.
In general, the agreement of chromosomal inversion topology with DNA sequence topology was extremely good.
Possessing chromosomes of varying shapes is generally the result of a chromosomal translocation or chromosomal inversion.
These areas are indicative of poor phylogenetic signal from one or both of the kinds of data - DNA and chromosomal inversion data.
He is also known for developing (along with others) a model wherein regions of restricted recombination, as by chromosomal inversions, facilitate the persistence of hybridizing species.
To suppress crossing over, balancer chromosomes are the products of multiple, nested chromosomal inversions so that synapsis between homologous chromosomes is disrupted.
The study of their antigen receptors lead to the discovery of chromosomal inversion during the formation of the T cell receptor (TCR).
By combining chromosomal translocation, chromosomal inversion,and chromosomal deletion, chromosome engineering has been shown to identify the underlying genes that cause certain diseases in mice.
The approach we have taken here is to combine the chromosomal inversion data with DNA sequence data to examine some of the classical notions of Drosophila evolution.
Materials and Methods Data matrices Four data matrices were constructed using DNA sequences and chromosomal inversion data from the literature (Table 1).
Some chromosome abnormalities do not cause disease in carriers, such as translocations, or chromosomal inversions, although they may lead to a higher chance of birthing a child with a chromosome disorder.
In 1919, Muller made the important discovery of a mutant (later found to be a chromosomal inversion) that appeared to suppress crossing-over, which opened up new avenues in mutation rate studies.
In order to assess the relative contribution of chromosomal inversion and DNA sequence data we placed our analysis in a simultaneous analysis framework [ 15 16 17 ] .
Chromosome abnormalities can be numerical, as in the presence of extra or missing chromosomes, or structural, as in chromosomal translocation, chromosomal inversion, large-scale deletions or duplications.