chromatolysis

Other cellular changes are observed during the process of the central chromatolysis.

By the 1970s, the conserved structural features of chromatolysis were identified.

Studies examining patients with alcoholic encephalopathies give evidence of central chromatolysis.

At this time, chromatolysis was proposed to play a major role in this physiological process.

It was also observed that the integrity of mitochondria is maintained during chromatolysis.

Part of this reaction includes structural alternations caused by the chromatolysis event.

Again, these expanded definitions of chromatolysis are consistent with what we now term apoptosis.

Exposure to lithium has also been used as a method to induce chromatolysis in rats.

Peripheral chromatolysis is much less common, but has been reported to occur after axotomy and ischemia in certain species.

Acrylamide intoxication has been shown to be an agent for the induction of chromatolysis.

The number of autophagic vacuoles and lysosomal structures often increase during central chromatolysis.

In addition to traumatic injuries, central chromatolysis may be caused by vitamin deficiency (pellagra).

The basophilic rim is formed as chromatolysis compresses the cytoplasmic skeleton.

Neuronal recovery through regeneration can occur after chromatolysis, but most often it is a precursor of apoptosis.

Flemming named this degenerative process "chromatolysis" to describe the gradual disintegration of nuclear components.

A second hypothesis proposes that blockage of axonal cytoskeletal proteins causes chromatolysis.

Examination of the trigeminal and dorsal root ganglia revealed peripheral chromatolysis in these cells.

In each case the neuron undergoes chromatolysis and atrophy of the cell body and axon.

The degenerate chromatolysis neurons seldom showed intracytoplasmic labeling for PrP.

The mechanisms and signals for chromatolysis were first researched in depth in the 1960s and still merit further investigation.

The nucleus of the damaged axon undergoes chromatolysis in preparation for axon regeneration.

Also characteristic of central chromatolysis is the displacement of the nucleus towards the periphery of the perikaryon.

Around the same time of Flemming's research, chromatolysis was also studied in the lactating mammary glands and in breast cancer cells.

Nissl bodies show changes under various physiological conditions and in pathological conditions they may dissolve and disappear (chromatolysis).

In 1952, research further supported the role of chromatolysis in changing the physiology of cells during cell death processes in embryo development.