The cause of death was amyloidosis, a rare auto-immune disease, which he had been battling for some months.
He calls Florence to take them to a vet, where they learn that the dog has an auto-immune disease.
It could be due to infection, auto-immune disease, or malignancy.
Hypersensitivity is believed to be the cause of allergy and some auto-immune disease.
Generally the immunology of most auto-immune diseases is not well understood.
However, no one knows what factor trigger the initiation of auto-immune disease like inflammation.
He said the studies did not ask about symptoms of auto-immune disease.
The team tells her to go outside, since extreme cold has been used as a treatment for auto-immune diseases.
But women in midlife are at higher risk of auto-immune diseases like lupus.
It most likely has a genetic component, as other auto-immune disease tend to run in the families of patients.