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The chondrogenic layer remains undifferentiated and can form chondroblasts or chondrocytes.
Osteoblastic and chondrogenic condensations differ in their biophysical parameters within the embryo.
It consists of two separate layers: an outer fibrous layer and inner chondrogenic layer.
While there are some differences (e.g. like the lack of chondrogenic progenitors), osseointegration occurs through the same mechanisms as bone fracture healing.
In contrast, the addition of transforming growth factor-beta (TGF-b) could induce chondrogenic markers.
The mesenchymal cells were placed in conditions that specified adipogenic, chondrogenic, or osteogenic conditions and differentiation.
Alcian Blue (Sigma) was used to detect extracellular matrix proteoglycans in chondrogenic cultures.
Chondrogenic differentiation was evident in the development of type II collagen that is seen in articular cartilage.
Miosge and his team said they examined the regenerative potential of chondrogenic progenitor cells present during the late stages of osteoarthritis.
Furthermore, MSCs can undergo osteogenic, adipogenic and chondrogenic differentiation ex-vivo.
Furthermore, these MSC can also be differentiated in-vitro into osteogenic, chondrogenic and adipogenic lineages.
Mouse dermal fibroblasts polygonal hyaline chondrogenic cells (Klf4, c-Myc, Sox9)
Various scaffold combinations with PEG-based hydrogels are studied to assess the chondrogenic response to dynamic strain stimulation in a recent study.
The chondrogenic cultures did not appear histologically to contain cells that were of the other lineages, but they did express osteopontin and alkaline phosphatase"."
As a proof of their existence, MCSs were successfully differentiated into the adipogenic, osteogenic and most importantly chondrogenic lineage.
An important genetic component of this process is Sox9, a HMG box transcription factor, which marks progenitor cells for chondrogenic differentiation.
The collagen membrane protects and stabilizes the MSCs released through microfracture and enhances their chondrogenic differentiation.
The protein encoded by this gene is involved in osteo- and chondrogenic cellular differentiation (the cells which are responsible for the development of bone and cartilage respectively).
This is supported by a study showing that knockdown of perlecan production inhibits the final stages of chondrogenic differentiation in C3H10T1/2 fibroblasts in culture.
As of 2013, urine-derived stem cells had been differentiated into endothelial, osteogenic, chondrogenic, adipogenic, skeletal myogenic and neurogenic lineages, without forming teratomas.
CYR61 also accelerates and promotes the chondrogenic differentiation of mouse limb bud mesenchymal cells, and stimulates osteoblast differentiation but inhibits osteoclastogenesis.
The role of QSulf1 was determined in quail cartilage development and joint formation because of its association with chondrogenic growth factor signaling (Wnt and BMP).
After differentiation, BMP4 and FGF2 treated cells generally produces higher amounts of osteogenic and chondrogenic differentiation than untreated stem cells.
Under proper induction culture in vitro or proper environment in vivo, DFAT cells could demonstrate adipogenic, osteogenic, chondrogenic, and myogenic potentials.
These chondrogenic cells differentiate into so-called chondroblasts, which then synthesize the cartilage extra cellular matrix (ECM), consisting of a ground substance (proteoglycans, glycosaminoglycans for low osmotic potential) and fibers.