chiral centre BrE technical
chiral center AmE technical

It also means that the sulfur can be a chiral centre.

Sometimes even if there is no chiral centre, some atoms may be used as having chirality.

When only one chiral centre is changed at a time, sets of diastereoisomers are formed.

This is because they have one chiral centre.

With only one chiral centre, there are two enantiomers.

Every chiral centre in a molecule has two possible ways of putting the groups in space.

If all four atoms attached to the considered atom have different priorities, it is a chiral centre.

The heavier halogens move the centre of mass nearer the chiral centre.

Glyceraldehyde has one chiral centre.

Each of the β-blockers possesses at least one chiral centre and a high degree of enantioselectivity when binding to the β-adrenergic receptor.

Each of the amino acids in lanreotide contains at least one chiral centre; therefore a number of linear and cyclic diastereoisomers could potentially be formed.

EPIMERS - Two diastereoisomers that have a different configuration at only one chiral centre.

Characterization Pantoprazole magnesium is a white to beige powder dihydrate only slightly soluble in water which possesses a chiral centre at the sulfur atom.

To determine whether a chiral centre is R (Latin: rectus) or S (Latin: sinister) first use the sequence rules to assign priorities.

For those β-blockers containing a single chiral centre, the (-) enantiomer has a much higher affinity in binding to the β-adrenergic receptor than the (+) enantiomer.

For venlafaxine there is only one chiral centre, although for the PRC compounds, there is a diastereoisomeric pair of racemers to consider.

Pharmacokinetics: Both S- and R-omeprazole are pro-drugs, which are converted within the parietal cell to the active proton pump inhibitor, which lacks a chiral centre.

With this chiral resolution, he was able to prove that not only carbon but also nitrogen atoms can be the chiral centre in a molecule, which was speculated for several years.

EPIMERIZATION - The change of configuration at a chiral centre in a molecule containing two or more chiral centres.

Thalidomide is racemic; the individual enantiomers can racemize due to the acidic hydrogen at the chiral centre, which is the carbon of the glutarimide ring bonded to the phthalimide substituent.

In general, the designation of D- or L- is determined by the orientation of the chiral centre which is most distant from the reference group (the aldehyde or ketone group for sugars).

They also all have a chiral centre on the alpha carbon (where the R1 group is attached) and so have two stereoisomers, with the dextro isomer being the more potent in all cases, although both isomers are active.

The 1,2-rearrangement has been shown to conserve the stereochemistry of the chiral centre as the product formed from t-BOC protected (S)-phenylalanine retains the (S) stereochemistry with a reported enantiomeric excess of at least 99%.

The measurement of the pitch length at constant temperature has been accomplished for the whole range of relative composition of the two different single chiral centre amphiphiles at constant water content and with all other components unchanged in composition.

For drug substances that contain a chiral centre, where there has not been any information provided regarding the manufacture of the starting material through which it has been introduced, results of chiral HPLC analyses should be submitted on enantiomeric purity/ratio of the drug substance.

This is a very good way to create new chiral centres.

It also means that the sulfur can be a chiral centre.

The Sketcher will try to find chiral centres and list them.

With two chiral centres, you can form 4 different isomers.

For the latter, clearly indicate all known chiral centres and those which are still unknown.

Internal return was also examined by racemization of the chiral center in 12a and 12d.

Sometimes even if there is no chiral centre, some atoms may be used as having chirality.

It is a 20-carbon alkaloid with six rings and seven chiral centres.

When only one chiral centre is changed at a time, sets of diastereoisomers are formed.

Chiral centres are a property of atoms with sp3 hybridisation.

Still other enzymes produce new chiral centers, always with a high specificity.

This is because they have one chiral centre.

With only one chiral centre, there are two enantiomers.

• The Scope could be interpreted to cover drugs with several chiral centres.

It is particularly useful for the classification of carbohydrates, which can have multiple chiral centres.

The absolute stereochemistry at several chiral centers has been determined as of 2009.

Every chiral centre in a molecule has two possible ways of putting the groups in space.

Users should check that all the chiral centres have been found, especially if the input coordinates are poor.

If all four atoms attached to the considered atom have different priorities, it is a chiral centre.

Styrene oxide has a chiral center and thus two enantiomers.

It is the simplest of all ketoses and has no chiral center or optical activity.

There are 3 major rules in finding the relative priority of the atoms attached to the chiral centres.

It can be synthethised chemically and possesses two chiral centers.

Having two chiral centers may give a meso compound which is achiral.

The ketohexoses have 3 chiral centres and therefore eight possible stereoisomers (2).