centrilobular

It may also be seen in older people with centrilobular emphysema.

Both centrilobular and paraseptal emphysema may progress to bullous emphysema.

Obstruction also causes centrilobular necrosis and peripheral lobule fatty change due to ischemia.

Centrilobular necrosis occurs.

Conversely, the centrilobular zone III has the poorest oxygenation, and will be most affected during a time of ischemia.

Zone 3 (centrilobular) occurs with ischemic injury, toxic effects, carbon tetrachloride exposure or chloroform ingestion.

Centriacinar (or centrilobular) emphysema: The respiratory bronchiole (proximal and central part of the acinus) has expanded.

Panacinar emphysema typically affects the lower lungs, while centrilobular emphysema affects the upper lungs.

The only microscopic lesion seen in mice was centrilobular hepatocellular hypertrophy, observed in two high-dose females and considered due to enzyme induction.

The liver histology in this syndrome shows Kupffer cell exfoliation, centrilobular accumulation of cellular debris, and panlobular congestion, especially in central areas.

However, it is more commonly classified by location into panacinary and centroacinary (or panacinar and centriacinar, or centrilobular and panlobular).

Chronic congestion in the centrilobular region of the liver leads to hypoxia and fatty changes of more peripheral hepatocytes, leading to what is known as nutmeg liver.

The main pathological changes were vacuolation of the neurons and axons in the spinal cord, with necrosis of the centrilobular hepatocytes and renal convoluted tubules and glomeruli.

The type of emphysema caused by A1AD is known as panacinar emphysema (involving the entire acinus) as opposed to centrilobular emphysema, which is caused by smoking.

CT scans were used by a radiologist to separate participants on the basis of the presence or the absence of any objective evidence for centrilobular, panacinar, or paraseptal emphysema with a detection limit of greater than 3-mm low attenuation density [34].

Lesions comprised perineuronal vacuolation in the gray matter of the spinal cord at the sacral region, centrilobular hepatocellular necrosis, degeneration of the renal proximal convoluted and collecting tubules, serous atrophy of the cardiac fat and renal pelvis and straw-coloured fluid in serious cavities.