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It is most commonly accomplished using the method of centrifugal sedimentation.
Centrifugal sedimentation is the most used process by which erythrocytapheresis occurs.
The particulate fraction was separated from the cytosolic compartment first by permeabilization using digitonin, followed by rapid centrifugal sedimentation through a bromododecane layer.
Isolation of the FeMo cofactor from nitrogenase is done through centrifugal sedimentation of nitrogenase into the MoFe protein and the Fe protein.