It is believed that these cell-surface receptors are responsible for the removal of certain glycoproteins from the circulatory system.
In the end, cell-surface receptors close the loop by giving feedback on the surrounding ECM to the cells, affecting also their gene expression level.
When interleukin-1 is produced in response to external stimuli, it can bind to cell-surface receptors on the same cell that produced it.
In general, cell-surface receptors have normal functions important to the body.
Ig-like domains are involved in a variety of functions, including cell-cell recognition, cell-surface receptors, muscle structure and the immune system.
The primary extracellular matrix components and cell-surface receptors which aid in metastasis are discussed here:
Growth factors cell-surface receptors:
Initially, platelets stick to the exposed connective tissue through specific cell-surface receptors.
Signal transduction involves the binding of extracellular signalling molecules and ligands to cell-surface receptors that trigger events inside the cell.
They switch on cell-surface receptors which activate T cells and B cells to start and shape the adaptive immune response.