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Activity is initiated by the pacemaker cells (interstitial cells of Cajal).
For the cell in the gastrointestinal tract, see Interstitial cell of Cajal.
The stimulation for these contractions likely originates in modified smooth muscle cells called interstitial cells of Cajal.
In the gastrointestinal smooth muscle, a slow wave originates in the cells of Cajal as the basal electrical rhythm.
Slow waves are initiated by pacemakers - the interstitial cells of Cajal (ICC).
Interstitial cell of Cajal (ICC)
He discovered a new type of cell, to be named after him: the interstitial cell of Cajal (ICC).
The interstitial cells of Cajal are specialized pacemaker cells located in the wall of the stomach, small intestine, and large intestine.
In addition, mast cells, melanocytes in the skin, and interstitial cells of Cajal in the digestive tract express CD117.
Smooth muscle may contract spontaneously (via ionic channel dynamics) or as in the gut special pacemakers cells interstitial cells of Cajal produce rhythmic contractions.
The interstitial cells of Cajal are named after Santiago Ramón y Cajal, a Spanish pathologist and Nobel laureate.
These cells, known as interstitial cells of Cajal, are part of the autonomic nervous system, which helps to control the movement of food and liquid through the stomach and intestines.
GISTs are thought to arise from interstitial cells of Cajal (ICC), that are normally part of the autonomic nervous system of the intestine.
They named these cells ICLC because of the apparent similarity, at first glance, with the canonical gastrointestinal interstitial cells of Cajal (ICC).
In dogs, LAC type activity has been recorded originating from the interstitial cells of Cajal located at the submucosa-circular muscle interface of the colonic wall, where pacemaking takes place.
Yukihiko Kitamura for "Development and Malignant Transformation of Mast Cells and Interstitial Cells of Cajal through KIT Receptors"
The interstitial cell of Cajal (ICC) is a type of interstitial cell found in the gastrointestinal tract that serves as a pacemaker which creates the bioelectrical slow wave potential that leads to contraction of the smooth muscle.