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Depending on the machine's design, either an anionic or a cationic detergent is used.
Cationic detergents : ionise in solution with the active ion being positively charged.
Quaternary ammonium compounds : are cationic detergents with disinfection properties.
They are often classified according to the charge of the molecule or ion, the three main classes being anionic, neutral, and cationic detergents.
The salt of a cationic detergent, undecoylium chloride is often complexed with iodine to form a topical antibiotic.
Not all cationic detergents, even those termed quaternary ammonium compounds, are capable of disinfecting although they have commercial uses as fabric softeners and conditioners.
Bactericidal products may be cationic detergents consisting of QAC-bisguanide combinations or liquid soaps compounded with disinfectant.
For example, beta-lysine, a protein produced by platelets during coagulation, can cause lysis of many Gram-positive bacteria by acting as a cationic detergent.
Several detergents were tested for their effects on cytoskeletal structures by Schliwa et al. [ 3], but the cationic detergent DOTMAC was not included.
Formed as a complex of iodine with undecoylium chloride, undecoylium chloride iodine is a cationic detergent typically used as a topical antigermicidal agent.
Interestingly, PIPs could be substituted for by a cationic detergent, dodecyltrimethylammonium chloride (DOTMAC) in vitro [ 19].
Cationic detergents are similar to the anionic ones, with a hydrophobic component, but, instead of the anionic sulfonate group, the cationic surfactants have quaternary ammonium as the polar end.
The fatal dose in humans ingesting cationic detergents has been estimated to be 1 to 3 g. Therefore, a person using a typical oral ingestible product that provides 0.25 mg CPC per dose will need to take 4000 doses at one time before they would be in the estimated fatal dose range.