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The actinide elution sequence is reversed from that of the cation-exchange resin column.
A cation-exchange resin column (Dowex-50 exchange column) treated with ammonium salts is then used to separate fractions containing elements 99, 100 and 101.
Insoluble microgranular CMC is used as a cation-exchange resin in ion-exchange chromatography for purification of proteins.
The elution of Md just before Fm in the elution sequence of the trivalent actinides from the cation-exchange resin column, confirmed this prediction.
Cations are replaced with hydrogen ions using cation-exchange resins; anions are replaced with hydroxyls using anion-exchange resins.
Separation of trivalent actinides from lanthanide fission products can be done by a cation-exchange resin column using a 90% water/10% ethanol solution saturated with hydrochloric acid (HCl) as eluant.
The cation-exchange resin column as well as the HDEHP solvent extraction column elution date is consistent with a trivalent state for Md and an ionic radius smaller than Fm.
The MCSGP process can result in purities and yields comparable to those of purification using Protein A. The second application example for the MCSGP prototype is the separation of three MAb variants using a preparative weak cation-exchange resin.