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For an animal who already has the problem, vitamin C sometimes helps, because it helps to stimulate cartilage formation.
The most common defect is achondroplasia, where there is a defect in cartilage formation.
In some cases a pseudo-joint (pseudarthrosis) develops between the two fragments with cartilage formation and a joint cavity.
Professor Hall has researched and extensively written on bone and cartilage formation in developing vertebrate embryos.
These growth factors modulate the differentiation of progenitor cells into osteoprogenitor cells, which are responsible for bone and cartilage formation.
Disruption of these pathways leads to abnormal bone and cartilage formation causing Acrania and multiple other craniofacial patterning problems.
Abnormal bone and cartilage formation caused the sternum--the breast bone--to be sunken in.
Sclerostin anatagonizes the activity of BMP (bone morphogenetic protein),a citokine that induces bone and cartilage formation.
The disorder itself is caused by a change in the DNA for fibroblast growth factor receptor 3 (FGFR3), which causes an abnormality of cartilage formation.
In addition, BMP4 has been shown to induce the expression of the Msx gene family, which is believed to be part of cartilage formation from somitic mesoderm.
To examine this function in more detail, we employed a culture system that facilitates chondrocyte maturation and cartilage formation, and closely recapitulates the in vivo situation [ 11 ] .
Chondrification (also known as chondrogenesis) is the underlying process of cartilage formation from condensed mesenchyme tissue, which differentiates into chondrocytes and begins secreting the molecules that form the extracellular matrix, the cartilage repair tissue.
Intra-articular snapping hip syndrome is often indicative of injury such as a torn acetabular labrum, recurrent hip subluxation, ligamentum teres tears, loose bodies, articular cartilage damage, or synovial chondromatosis (cartilage formations in the synovial membrane of the joint).
Paste grafting involves replacing damaged cartilage with autologous cartilage and cancellous bone from the intercondylar notch in the center of the knee that is first morselized into a paste (typically with hydroxyapatite) to better fill the defect and more successfully promote chondrocyte activity and cartilage formation.
Bone morphogenetic proteins (BMPs) are a subgroup of TGF-β superfamily that can induce bone and cartilage formation as well as tissue differentiation, and BMP-12 specifically has been shown to influence formation and differentiation of tendon tissue and to promote fibrogenesis.
Elations, a new flavored beverage from a company run by a team of former Procter & Gamble executives, promises "joint flexibility" and contains the nutritional supplements glucosamine, which is believed to play a role in cartilage formation and repair, and chondroitin, a natural component of cartilage that is thought to help with elasticity.