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They view the cardiorenal syndrome in a more holistic, integrative manner.
He characterized the cardiorenal syndromes that emerge in clinical practice in patients using analgesics and NSAIDs.
They defined the cardiorenal syndrome as a pathophysiological condition in which combined heart and kidney dysfunction amplifies progression of failure of the individual organ, by inducing similar pathophysiological mechanisms.
Cardiorenal syndrome (CRS) is an umbrella term used in the medical field that defines disorders of the heart and kidneys whereby "acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other".