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In this fashion, paracetamol acts as a pro-drug for a cannabimimetic metabolite.
CB antagonists produce inverse cannabimimetic effects that are opposite in direction from those produced by agonists for these receptors.
Likewise, there was no difference between ajulemic acid and placebo on the "cannabimimetic" assay when used in humans at therapeutic doses.
Beta-caryophyllene was shown to be selective agonist of cannabinoid receptor type-2 (CB) and to exert significant cannabimimetic antiinflammatory effects in mice.
The part adding to Schedule I various "cannabimimetic agents" which include molecules more closely resembling so-called "classically" structured cannabinoids reads as follows:
However, AB-001 was found to possess only weak cannabimimetic effects in rats at doses up to 30 mg/kg, making it less potent than the carboxamide analogue APICA, which possesses potent cannabimimetic activity at doses of 3 mg/kg.