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Their biological availability to the body depends upon dihydrofolate reductase action in the liver.
Different proteins have different levels of biological availability (BA) to the human body.
These salts need to have a high 'Biological Availability' ie the horse has to be able to efficiently digest and absorb the minerals.
Another concern is that acid deposition may accelerate the leaching, mobilization and enhanced biological availability of toxic heavy metals and other toxic chemicals in past, present and future hazardous waste (and other solid waste) landfills.
Furthermore, abiotic transformation in the extended microbial loop depends only on temperature and the capacity of DOM to aggregate, while biotic transformation is dependent on its biological availability (Kerner, Hohenberg, Ertl, Reckermannk, Spitzy 2003).