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However, there is currently insufficient information to conclusively link ochratoxin A to Balkan endemic nephropathy.
Later, following descriptions of similar ailments in Yugoslavia and Romania, the condition became known as Balkan endemic nephropathy.
The toxin may require synergistic interactions with predisposing genotypes or other environmental toxicants to induce Balkan endemic nephropathy.
Aristolochic acids are hypothesized to be causative agents in Balkan endemic nephropathy; and a related-possibly identical-condition known as "Chinese herbs nephropathy".
Balkan Endemic Nephropathy is a slowly progressive renal disease that appeared in the middle of the 20th century, highly localized around the Danube, but only hitting certain households.
Danubian endemic familial nephropathy (DEFN), also called Balkan endemic nephropathy, is a form of interstitial nephritis.
A number of descriptive studies have suggested a correlation between exposure to ochratoxin A and Balkan endemic nephropathy, and have found a correlation between the geographical distribution of Balkan endemic nephropathy and a high incidence of, and mortality from, urothelial urinary tract tumours.