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Sparfloxacin, like other quinolones and fluoroquinolones, are bactericidal drugs, actively killing bacteria.
Quinolones and fluoroquinolones are chemotherapeutic bactericidal drugs, eradicating bacteria by interfering with DNA replication.
For treatment of drug-resistant TB, a minimum of three drugs should be administered, including two or more bactericidal drugs to which the isolate is susceptible (AII).