Its intended uses include reducing physiological stress such as due to being transported, and preventing azoturia in performance animals.

These include the risks of developing splints, joint damage due to overweight in young horses, founder, and azoturia in working horses.

The Equine Research Station in Newmarket is currently carrying out research into azoturia (set-fast, tying-up, etc.)

Equine exertional rhabdomyolysis (ER, also known as tying up, azoturia, or Monday morning disease) is a syndrome that damages the muscle tissue in horses.

Equine Exertional Rhabdomyolysis, also known as "tying up" or azoturia, is a condition to which only some horses are susceptible and most cases are linked to a genetic mutation.

At the same track on April 26 he finished last of the six runners in the Chesapeake Stakes, after which he was reported to be suffering from a kidney ailment described as "azoturia" or "blackwater".

Following an HYPP attack, the horse appears normal and is not in any pain which helps to distinguish it from Equine Exertional Rhabdomyolysis (ER), commonly known as "Azoturia," "Monday Morning Sickness" or "tying up."