asymmetric induction

He also did work in stereochemistry and Cram's rule of asymmetric induction is named after him.

Reaction progress can also be influenced through conformational control and often exhibit asymmetric induction.

Asymmetric induction can occur intramolecularly when given a chiral starting material.

Chiral ligands work asymmetric induction somewhere along the reaction coordinate.

Torquoselectivity is a discrimination between these possible enantiomers that requires asymmetric induction.

It has been observed that the stereoelectronic environment at the β-carbon of can also direct asymmetric induction.

Asymmetric induction is a key element in asymmetric synthesis.

The N-sulfinyl group exerts powerful and predictable stereodirecting effects resulting in high levels of asymmetric induction.

This has been extensively studied, and in many cases, one can predict the sense of asymmetric induction, if not the absolute level of diastereoselectivity.

This type of preferential formation of one enantiomer or diastereomer over the other is formally an asymmetric induction.

Anh's solution was to offer the antiperiplanar effect as a consequence of asymmetric induction being controlled by both substituent and orbital effects.

The asymmetric induction approach relies on stereocenters already set in the starting material that are unaffected by the reaction (chiral auxiliaries).

Asymmetric versions of the above reaction have taken advantage of a number of strategies for achieving asymmetric induction.

Internal asymmetric induction makes use of a chiral center bound to the reactive center through a covalent bond and remains so during the reaction.

However, despite its prevalence asymmetric induction is not always required for enantioselective synthesis, with the most obvious example being in chiral pool synthesis.

Chiral pool synthesis is one of the simplest approaches for enantioselective synthesis, as it does not involve asymmetric induction.

The ligand was an important demonstration of how the conformation of the chelate ring can affect asymmetric induction by a metal catalyst.

In external asymmetric induction chiral information is introduced in the transition state through a catalyst of chiral ligand.

On approach to the lithium intermediate, the bulky tosyl group on the imine electrophile is responsible for the asymmetric induction taking place.

Asymmetric induction in transition metal catalyzed reactions is achieved through the use of a chiral Lewis basic ligand in catalytic amounts.

Asymmetric induction may be conferred by chiral PYBOX ligands.

In relayed asymmetric induction the chiral information is introduced in a separate step and removed again in a separate chemical reaction.

Both inter- and intramolecular insertions are amendable to asymmetric induction by choosing chiral ligands on metal centers.

Ruppert's reagent has been used for this purpose in an asymmetric induction approach to functionalise chiral amino acid derivates, carbohydrates, and steroids.

The catalysts were found to afford high levels of asymmetric induction in several processes, including the ene reaction of ethyl glyoxylate with different unactivated olefins.