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There are many speculations as to what is the main cause of astasis.
One study described a patient with astasis as lying in bed with a normal body posture.
Abasia is frequently accompanied by astasis, an inability to stand, see Astasia-abasia.
Damage to the peripheral nerves coming from the legs to the somatosensory area is the leading candidate for the cause of astasis.
Since astasis itself is more a symptom than a disease, it is more often seen associated with other signs and symptoms.
These damaged nerves prevent feedback for stabilization of posture for patients with astasis.
Weakness of the triceps surae muscle has been seen in many patients who have been diagnosed with astasis.
This indicates that weakness to this muscle is the cause of the swaying and impaired posture in patients with astasis.
Depending on where the abnormality is in a patient they can experience a wide range of symptoms, including those that are found in patients with astasis.
Paul Oscar Blocq was the first to describe astasis as the inability to maintain an upright posture despite normal function of the legs while sitting.
The term "astasia" is interchangeable with "astasis" and is most commonly referred to as astasia in the literature describing it.
The disturbance differs from cerebellar ataxia in the fact that with astasis the gait can be relatively normal, with balance significantly impaired during transition from a seated to standing position.
Diabetes, spinal root or spinal cord lesions, and traumas or injuries to the motor cortex of the brain can also cause similar symptoms that are seen in patients with astasis.
This region of the brain is not yet well understood and according to current knowledge, this is the first reported case with the simultaneous combination of astasis, pretectal syndrome, and asymmetrical asterixis.
Jean-Martin Charcot, Charles Lasègue, and other physicians prior to Blocq's description described astasis as "a special variety of motor feebleness of the legs from want of coordination in standing position."