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Fine-needle aspiration cytology can also be used to confirm the diagnosis.
Percutaneous fine needle aspiration cytology is, however, highly operator dependent.
Aspiration cytology of the neck mass showed only amorphous, necrotic material.
Finally, to achieve a definitive diagnosis before deciding on treatment, a fine needle aspiration cytology test is usually performed.
The commonly used diagnostic procedures for skin tumors are fine-needle aspiration cytology and tissue biopsy.
In 1949 Lemon and Byrne reported a large series of patients undergoing duodenal aspiration cytology with a test sensitivity of over 70%.
The possible dissemination of tumour by percutaneous fine needle aspiration cytology may result in these becoming the diagnostic techniques of choice.
Unlike duodenal aspiration cytology, bile exfoliative cytology is generally 100% specific (no false positive results).
In many cases, the diagnosis of breast carcinoma using core needle biopsy or fine-needle aspiration cytology may be sufficient to confirm malignancy.
Microfilaria concomitant with metastatic deposits of adenocarcinoma in lymph node fine needle aspiration cytology: A chance finding.
Although lymph node biopsies are recommended whenever possible, sometimes immunophenotypic data are sufficient to allow diagnosis of lymphoma when fine-needle aspiration cytology is preferred.
If fine needle aspiration cytology (FNAC) suggests follicular neoplasm, thyroid lobectomy should be performed to establish the histopathological diagnosis.
Surprisingly the sensitivity reported for this technique is frequently less than that for duodenal aspiration cytology, although this may be related to differences in the stage of disease being investigated.
Histological examination of tissue attained by fine needle aspiration cytology may demonstrate dilated ducts with periductal fibrosis, increased subareolar fat, and hyalinization of the stroma.
Stevens C, Lee JK, Sadatsafavi M, et al.: Pediatric thyroid fine-needle aspiration cytology: a meta-analysis.
The morbidity and mortality associated with percutaneous biopsy is very low, and with the use of a fine needle for aspiration cytology is negligible (about 0.16% and 0.006% respectively).
Both endobiliary biopsy and endobiliary fine needle aspiration cytology are likely to establish a role in the investigation of patients in whom a tissue diagnosis is elusive by standard methods.
Young NA, Al-Saleem T: Diagnosis of lymphoma by fine-needle aspiration cytology using the revised European-American classification of lymphoid neoplasms.
Despite this theoretical risk, the possibility of safely establishing a tissue diagnosis in about two thirds of patients with a focal lesion on imaging justifies percutaneous aspiration cytology as a first line investigation.
Fabian CJ, Kimler BF, Zalles CM, et al.: Short-term breast cancer prediction by random periareolar fine-needle aspiration cytology and the Gail risk model.
Percutaneous aspiration cytology has been reported as confirming malignancy in about two thirds of pancreatic cancers and one half of bile duct tumours but cannot be done unless a mass lesion is established on imaging.
Aspiration cytology alone is not recommended because of the lack of stromal tissue, the small number of cells present in the specimen, and the difficulty of classifying Hodgkin lymphoma into one of the subtypes.
Before percutaneous fine needle aspiration cytology was attempted many groups had shown that a tissue diagnosis could be achieved in some patients with obstructive jaundice caused by malignancy by detecting neoplastic cells in duodenal aspiration.
Based on fair evidence, screening would result in rare but serious side effects associated with needle aspiration cytology such as needle-track seeding, particularly of lesions more than 2 cm in diameter, and hemorrhage, bile peritonitis, and pneumothorax.
Fine-Needle Aspiration Cytology or Needle aspiration biopsy - A needle attached to a syringe is used to collect cells from lesions or masses in various body organs by microcoring, often with the application of negative pressure (suction) to increase yield.