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Other diuretics have been known for a long time, especially arsenical compounds of mercury.
Arsenical compounds are one possibility.
Those with arsenical compounds were almost never sold to consumers anyway; they were used primarily by manufacturers to produce pressure-treated lumber.
These arsenical compounds came with considerable risk of side effects, and they were supplanted as treatments for syphilis in the 1940s by penicillin.
Arsenical compounds were effective in killing larvae but were considered too toxic for human contact even in the early 20th century.
Ehrlich's laboratory developed a more soluble (but slightly less effective) arsenical compound, Neosalvarsan (neoarsphenamine), which was easier to prepare, and it became available in 1912.
"It is possible that Iraq produces other chemical agents as well, including phosgene, arsenical compounds and cyanide compounds," Mr. Carus said.
The authors of both previous pilot studies of bismuth in colitis were prompted to use the heavy metal because of previous reports of benefit with arsenical compounds.
In reality, only certain wood preservatives were included in the ban -those containing creosote, pentachlorophenol (usually referred to as penta) and those containing certain inorganic arsenical compounds.
As arsenical compounds are notably toxic and carcinogenic-with side effects such as cirrhosis of the liver, idiopathic portal hypertension, urinary bladder cancer, and skin cancers-Fowler's solution fell from use.
Sahachiro Hata and Paul Ehrlich discovered the antisyphilitic activity of this compound in 1909 in the laboratory of Paul Ehrlich, during a survey of hundreds of newly synthesized organic arsenical compounds.