Aneuploid cells are more likely to spread than diploid cells.

Alternatively, nuclei may lose some chromosomes, resulting in aneuploid cells.

Level of mosaicism: There is a correlation between a high number of aneuploid cells detected at CVS with poor pregnancy progress.

In cancerous cells, over-expression of these enzymes causes unequal distribution of genetic information, creating aneuploid cells, a hallmark of cancer.

The underlying cause of aneuploidy remains highly debated; however, entosis is shown to perturb cytokinesis (cytoplasmic division) and trigger the formation of aneuploid cells.

Adverse prognostic features associated with a greater risk of disease progression include the presence of multiple aneuploid cell lines, nuclear p53 overexpression, and expression of the Lewis-x blood group antigen.

Cells which fail to go through a mitotic catastrophe after a mitotic failure are likely to create aneuploid cells when they later reproduce, posing a risk of oncogenesis, potentially leading to cancer.