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People with type 1 diabetes do not make amylin themselves.
Lilly was developing a drug similar to Amylin's on its own.
Type 1 diabetics do not produce amylin on their own, either.
"But amylin acts to slow the inflow into the blood.
Four years ago, Amylin laid off 80 percent of its employees and nearly closed after running into problems with its first drug.
His action ended up being good not only for Amylin and diabetics, but also for him.
Like insulin, amylin is completely absent in individuals with Type I diabetes.
Some researchers discourage the use of "amylin" on the grounds that it may be confused with the pharmaceutical company.
As the blood sugar level comes back toward normal, the beta cells will stop spurting insulin and amylin.
To control blood sugar levels, the pancreas secretes two hormones, insulin and amylin.
The function of amylin is to slow the rate of glucose entering the bloodstream.
He is now chief executive of the Amylin Corporation in San Diego.
Lifescan could also make additional equity investments of $30 million, depending on whether Amylin reached certain development milestones.
There appear to be at least three distinct receptor complexes that bind with high affinity to amylin.
Among other effects, Amylin delays gastric emptying and promotes a feeling of satiety.
Mr. Andersson invested $6 million at a time when Amylin's stock was selling for about $1.
The timing was fortuitous for Amylin.
This hormone was named exendin-3 and is marketed by Amylin Pharmaceuticals as the drug exenatide.
Other hormones produced include somatostatin, pancreatic polypeptide, amylin and ghrelin.
Rodent amylin knockouts are known to fail to achieve the normal anorexia following food consumption.
Both the amidated C-terminus and the disulfide bridge are necessary for the full biological activity of amylin.
AC137 mimics the effects of amylin, a recently discovered hormone that appears to be a biological partner of insulin.
The drug was developed by Amylin Pharmaceuticals and Eli Lilly.
Many diabetics are deficient in Amylin.
The effect of amylin is to spread out the blood glucose peak after eating, reducing the quantity of insulin needed.