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The ameboma may manifest as a right lower quadrant abdominal mass, which may be mistaken for carcinoma, tuberculosis, Crohn's disease, actinomycosis, or lymphoma.
An ameboma, also known as an amebic granuloma, is a rare complication of entamoeba histolytica, where in response to the infecting amoeba there is formation of annular colonic granulation, which results in a large local lesion of the bowel.
Symptoms can include fulminating dysentery, bloody diarrhea, weight loss, fatigue, abdominal pain, and amoeboma.