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His doctoral thesis was on calcium and the alpha cells of the pancreas.
When blood glucose concentration falls to hypoglycemic levels, alpha cells release glucagon.
In rodents, the alpha cells are located in the outer rim of the islet.
Human islet structure is much less segregated, and alpha cells are distributed throughout the islet.
Alpha cells occur in pancreatic islets, mixed with beta and other cells.
As the glucose level approaches a low mark, the pancreatic alpha cells will release glucagon directly into the bloodstream.
It is the beta cells that produce the insulin, and the alpha cells produce the hormone with the opposing effect.
Doxorubicin and streptozotocin have also been used successfully to selectively damage alpha cells of the pancreatic islets.
These are both produced in the pancreas: insulin from beta cells and glucagon from alpha cells.
The pancreas has many islets that contain insulin-producing beta cells and glucagon-producing alpha cells.
Your pancreatic alpha cells secrete glucagon, and glucagon levels in your blood rise.
Glucagon is another protein hormone that is made and secreted by the alpha cells of the pancreatic islets.
Alpha cells are endocrine cells in the islets of Langerhans of the pancreas.
Alpha cells produce less glucagon in response to rising glucose levels, and more glucagon if blood glucose is low.
As expected, they also inhibit glucagon release from the alpha cells of the Islets of Langerhans.
Amylin slows gastric emptying, and also inhibits the release of glucagon from the pancreatic alpha cells.
The islets of Langerhans contain two varieties of cells, named alpha cells and beta cells.
When being viewed by an electron microscope, alpha cells can be identified by their characteristic granules with a large dense core and a small white halo.
GLP-1 also reduces the scretion of glucacon by pancreatic alpha cells, thereby resulting in a decreased hepatic glucose production.
GLP-1 also reduces glucagon secretion from pancreatic alpha cells, resulting in a reduction in hepatic glucose output.
A glucagonoma is a rare tumor of the alpha cells of the pancreas that results in up to a 1000-fold overproduction of the hormone glucagon.
While beta cells respond to rising glucose levels by secreting insulin, alpha cells respond by reducing glucagon secretion.
It is generated in the alpha cells of the pancreas and in the intestinal L cells in the distal ileum and colon.
It is known to suppress glucagon secretion from pancreatic alpha cells and stimulate insulin secretion by pancreatic beta cells.
The hormone is synthesized and secreted from alpha cells (α-cells) of the islets of Langerhans, which are located in the endocrine portion of the pancreas.