aldosterone receptor

Progesterone may also interact with the aldosterone receptor, thus leading to increased levels.

Aldosterone receptor antagonists to make the kidneys get rid of extra fluid.

Channel-inducing factor is a regulatory protein for aldosterone receptors.

Aldosterone receptor antagonists are the only diuretics that improve survival for people with heart failure.

Another type of diuretic called an aldosterone receptor antagonist may be an option for some people who have heart failure.

Aldosterone receptor antagonists are medicines that help the body get rid of extra water (diuretics).

Aldosterone receptor antagonists, such as spironolactone, are another type of potassium-sparing diuretic used for heart failure.

Sodium retention is also a response of the distal colon, and sweat glands to aldosterone receptor stimulation.

Aldosterone receptor antagonists:

Hypertension and hypokalemia can also be seen with a deficiency of the 11-beta-hydroxysteroid dehydrogenase type 2 enzyme which allows cortisols to stimulate aldosterone receptors.

Whereas β-blockers, diuretics, ACE inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists have been shown to improve outcome.

Spironolactone inhibits the effect of aldosterone by competing for intracellular mineralocorticoid receptor in the distal convoluted tubule cells (it actually works on aldosterone receptors in the collecting duct).

Drugs that interfere with the secretion or action of aldosterone are in use as antihypertensives, like Lisinopril; which lowers blood pressure by blocking the aldosterone receptor; its net effect is to reduce sodium and water retention, but increase retention of potassium.

The mineralcorticoid receptor is stimulated by both aldosterone and cortisol, but a mechanism protects the body from excess aldosterone receptor stimulation by glucocorticoids (such as cortisol), which happen to be present at much higher concentrations than mineralcorticoids in the healthy individual.

In addition to pharmacologic agents (oral loop diuretics, beta-blockers, ACE inhibitors or angiotensin receptor blockers, vasodilators, and in severe cardiomyopathy aldosterone receptor antagonists), behavioral modification should be pursued, specifically with regard to dietary guidelines regarding fluid intake.