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If an adrenal adenoma is identified it may be removed by surgery.
There were elevated levels of aldosterone in her circulation, coming from a hormone producing adrenal adenoma.
Secondary hypertension indicates that the high blood pressure is a result of another underlying condition, such as kidney disease or tumours (adrenal adenoma or pheochromocytoma).
Primary aldosteronism (hyporeninemic hyperaldosteronism) was previously thought to be most commonly caused by an adrenal adenoma, termed Conn's syndrome.
When it occurs due to a solitary aldosterone-secreting adrenal adenoma (a type of benign tumor), it is known as Conn's syndrome.
A adrenal adenoma is a benign tumor of the glandular type (adenoma) in the adrenal gland.
If plasma levels of renin and aldosterone suggest hyperaldosteronism, CT scanning can confirm the presence of an adrenal adenoma.
Neoplasms - Renal-cell carcinoma or liver tumors, von Hippel-Lindau disease, and endocrine abnormalities including pheochromocytoma and adrenal adenoma with Cushing's syndrome.
A high dose dexamethasone exerts negative feedback on pituitary ACTH producing cells but not on ectopic ACTH producing cells or adrenal adenoma.
Cosyntropin is also used in the opposite situation, when there is aldosterone hypersecretion due to either a unilateral adrenal adenoma (which is treated by surgical removal) or bilateral adrenal hyperplasia (treated by oral spironolactone).
A practical application of this is in evaluation of tumors, where, for example, an adrenal tumor with a radiodensity of less than 10 HU is rather fatty in composition and almost certainly a benign adrenal adenoma.
Elevated renin due to renal artery stenosis or a very rare renin-producing juxtaglomerular cell tumor of the kidney can produce secondary hyperaldosteronism (as apposed to primary hyperaldosteronism aka Conn syndrome, usually due to a functional adrenal adenoma).
There were only three main causes of the disease: the pituitary adenoma (an often benign tumor on the pituitary gland); an adrenal adenoma, which is a small, often undetectable, tumor on or inside the adrenal gland; or an adenoma in the lung, which is 95 percent undetectable.