adenosine receptor

In humans, there are four types of adenosine receptors.

Once the findings were made on adenosine receptors, people gave animals different doses of caffeine.

Several classes of adenosine receptors have been described, with different anatomical distributions.

Caffeine is known to block adenosine receptors, thereby inhibiting sleep among other things.

When the brains of such animals are examined, he said, they are found to contain many more adenosine receptors than normal.

It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.

Caffeine antagonizes benzodiazepines as well, though it is weaker than that of the adenosine receptors.

It is also employed the synthesis of an experimental adenosine receptor ligand.:

With adenosine receptors blocked by caffeine, the brain can't slow down, and you stay awake and alert.

Caffeine competitively inhibits different adenosine receptors and their associated G protein to make a person feel alert.

Studies have shown that drugs such as caffeine can suppress the effect of sleep inertia, possibly by blocking adenosine receptors in the brain.

At higher doses, caffeine blocks a majority of adenosine receptors and can produce anxiety and hypersensitivity to pain.

It acts as adenosine receptor agonist.

Over time, excess free adenosine down-regulates primary A1 adenosine receptors, leading to increased muscle pain.

All adenosine receptors were shown to activate at least one subfamily of mitogen-activated protein kinases.

Xanthines (e.g. caffeine) specifically block adenosine receptors, and are known to induce a stimulating effect to one's behavior.

In addition to these inactive-state structures, Stevens and colleagues solved the structure of an agonist-bound A adenosine receptor.

Caffeine antagonizes, or blocks, adenosine receptors.

However, instead of disappearing, it blocks the adenosine receptors so the brain's stimulants, dopamine and glutamate, can work more freely.

Both are G protein-coupled adenosine receptors:

The predominate mechanism of action of caffeine is the antagonism of adenosine receptors.

Unlike other xanthines, doxofylline lacks any significant affinity for adenosine receptors and does not produce stimulant effects.

Caffeine - noncompetitive (although an Adenosine receptor antagonist)

Adenosine mediates pain through adenosine receptors.

CPA is widely used in scientific research into the adenosine receptors and has been used to derive a large family of derivatives.