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This new bit of information leads to House developing a new theory, Henoch-Schönlein purpura as a result of a bee sting, which proves to be correct.
Henoch-Schönlein purpura (HSP, also known as anaphylactoid purpura, purpura rheumatica, and Schönlein-Henoch purpura) is a disease of the skin and other organs that most commonly affects children.
Note that not all cases of a purpura-like rash are due to meningococcal septicaemia; however, other possible causes need prompt investigation as well (e.g. ITP a platelet disorder or Henoch-Schönlein purpura).
There are other diseases associated with glomerular IgA deposits, the most common being Henoch-Schönlein purpura (HSP), which is considered by many to be a systemic form of IgA nephropathy.
A similar mechanism has been claimed to underlie Henoch-Schönlein purpura (HSP), a vasculitis that mainly affects children and can feature renal involvement that is almost indistinguishable from IgA nephritis.
Multiple standards exist for defining Henoch-Schönlein purpura, including the 1990 American College of Rheumatology (ACR) classification and the 1994 Chapel Hill Consensus Conference (CHCC).
Examples of pathognomonic findings include Koplik's spots inside the mouth in measles, the palmar xanthomata seen on the hands of people suffering from hyperlipoproteinemia, Negri bodies within brain tissue infected with rabies, or a tetrad of rash, arthralgia, abdominal pain and kidney disease in a child with Henoch-Schönlein purpura.