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The treatment of acute maxillary sinusitis is usually prescription of a broad-spectrum cephalosporin antibiotic resistant to beta-lactamase, administered for 10 days.
Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydophila pneumoniae), skin and skin structure infections.
There are specific drawbacks, however: for example, both tests for ESR and CRP were found to be independently associated with a diagnosis of acute maxillary sinusitis so in some cases the combination of the two measurements may improve diagnostic sensitivity and specificity.