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Some of the associated risks are from the leak of acrylic cement to outside of the vertebral body.
For example, you would use solvent or two-part acrylic cement to join two pieces of acrylic, but for mounting the acrylic on wood, you would need epoxy cement.
After some apparently successful experiments on the material, he adopted it for his hip replacement surgeries which were carried out as follows: discardation of the head of the femur; replacement with a metallic implant that was fixed with acrylic cement; and, using a PTFE socket, insertion of the implant into the acetabulum.