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Carroll suffered from severe, 2-dimensional spinal curvature (Kyphoscoliosis) and acromegalic gigantism.
Weidenreich considered acromegalic gigantism, but ruled it out for not having typical features such as an exaggerated chin and small teeth compared to the jaw's size.
He developed a pituitary gland tumor which caused the gland to secrete large amounts of growth hormone, resulting in what doctors describe as acromegalic gigantism.