acidic amino acids

A short stretch of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions.

In Halobacterium, the proteins in the wall have a high content of acidic amino acids, giving the wall an overall negative charge.

Notably the role of neutral and acidic amino acids was shown for the first time in contributing to the efficiency of the NLS.

Transactivation by the Gal4 transcription factor is mediated by acidic amino acids, whereas hydrophobic residues in Gcn4 play a similar role.

This deletion removes a cluster of acidic amino acids, similar to acidic activation domains known to activate transcription in a variety of eucaryotes [ 36].

Since acidic amino acids, such as aspartic acid and glutamic acid, are important mediators of biomineralization, shell proteins tend to be rich in these amino acids.

Clusters of acidic amino acids that function as transcriptional activation domains can also activate chromosomal DNA replication by interacting with replication protein A (RPA) [ 37].

CKI also phosphorylates a related unprimed site, which optimally contains a cluster of acidic amino acids N-terminal to the target S/T including an acidic residue at n 3 and a hydrophobic region C-terminal to the target S/T.