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A minimum of 9 base pairs can be changed using 3 zinc fingers.
One zinc finger can bind about 3 base pairs by itself.
These zinc fingers are thought to be involved in protein-protein interactions.
Early growth response proteins are a family of zinc finger transcription factors.
Zinc fingers are much more difficult to make.
This sequence is defined by 11 zinc finger motifs in its structure.
A short zinc finger protein fold has been redesigned this way.
Zinc finger protein 202 is a transcription factor first associated with breast cancer.
Additionally, zinc fingers have become extremely useful in various therapeutic and research capacities.
These zinc fingers can be found in several transcription factors including the yeast Gal4 protein.
It is a member of the Kruppel-type zinc finger transcription factor family.
The residues marked 'x' are not part of the zinc fingers, but rather serve to connect them all together.
Their secondary and tertiary structure is distinct from that of classic zinc fingers.
'Zinc finger' is the name of many protein structures.
A number of genome-wide associations such as zinc finger protein 804A have also been linked.
Several approaches are used to design specific zinc finger nucleases for the chosen sequences.
This zinc finger structure is uncommon in the way that it involves one histidine instead of two.
Three zinc fingers are positioned in a semi-circular or C-shaped arrangement.
In these two types of enzymes, the C-terminal domain forms a zinc finger.
It appears that the conserved basic residues, and not the zinc fingers, are important for complex formation.
B-box type 2 zinc finger and a coiled-coil region.
It was formed in 2008 to investigate zinc finger nuclease technology and its application for disease research models.
The protein encoded by this gene is a zinc finger transcription factor.
Based on previous research on binding sites, many were frequently involved with zinc finger proteins.
Shown below is an amino acid sequence alignment between two human zinc finger proteins.