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This recognition was done by a T-cell receptor on the surface of the T cell.
A few cases have shown rearrangement of the T-cell receptor β gene.
It also supports signaling from T-cell receptors.
Immature thymocytes each make distinct T-cell receptors by a process of gene rearrangement.
Normally T-cell receptor genes and antibody genes are arranged in many different patterns.
Circulating Sézary cells can be confirmed by T-cell receptor gene analysis.
T-cell receptor stimulation is the primary signal required for the activation and differentiation of T-cells.
The majority of cases, greater than 90%, contain a clonal rearrangement of the T-cell receptor.
Immature thymocytes undergo a process of selection, based on the specificity of their T-cell receptors.
It may occur with help from stimulatory molecules located at the cell surface of other cells, as with T-cell receptor signaling.
Mixed lymphocyte reaction T-cell receptors.
They determined that one type of T-cell receptor predominated in the rally against proteins on the surface of myelin tissue.
Characterized by clonal T-cell receptor gene rearrangement, this entity is managed like diffuse large cell lymphoma.
Researchers identified the maturation promoting factor that regulates cell division, and discovered the T-cell receptor which trigger responses of the immune system.
At this stage they must create a unique T-cell receptor through V(D)J recombination.
The most accepted hypothesis is that dialogue between T-cell receptors and myelin antigens leads to an immune attack on the myelin-oligodendrocyte complex.
T-cells may recognize these complexes using their T-cell receptors (TCRs).
They looked at 100,000 genetic bases that make up the gene responsible for the body's production of the T-cell receptor, a critical part of the immune system.
Both are required for production of an effective immune response; in the absence of co-stimulation, T-cell receptor signalling alone results in anergy.
Clonal rearrangement of the γ gene of the T-cell receptor is the hallmark of this disease.
Uveitis is driven by the Th17 T cell sub-population that bear T-cell receptors specific for proteins found in the eye.
When the scientists analyzed tissue from the patients' brain lesions, they expected to find 20 different T-cell receptor types, but to their astonishment they identified only four.
Knowledge of cell surface markers and immunoglobulin and T-cell receptor gene rearrangements may help with diagnostic and therapeutic decisions.
T-cells are able to distinguish between self and non-self largely through their T-cell receptor, or TCR.
T-cell receptor alpha chain C region is a protein that in humans is encoded by the TRA@ gene.