Parry-Romberg syndrome
progressive hemifacial atrophy

Parry-Romberg syndrome appears to occur randomly and for unknown reasons.

The severity and specific symptoms of Parry-Romberg syndrome are highly variable from one person to another.

The majority of individuals with Parry-Romberg syndrome experience symptoms before the age of 20 years.

Parry-Romberg syndrome usually becomes apparent during the first decade of life or early during the second decade.

Enophthalmos (recession of the eyeball within the orbit) is the most common eye abnormality observed in Parry-Romberg syndrome.

The tissues of the mouth, including the tongue, gingiva, teeth and soft palate are commonly involved in Parry-Romberg syndrome.

The exact cause of Parry-Romberg syndrome is unknown; cases appear to occur randomly for unknown reasons (sporadically).

Miller's contributions include descriptions of ocular findings in Mobius syndrome, Parry-Romberg syndrome, and fetal alcohol syndrome.

The test was named after the German neurologist Moritz Heinrich Romberg (1795-1873), who also gave his name to Parry-Romberg syndrome and Howship-Romberg sign.

The fact that some people affected with this disease have circulating antinuclear antibodies in their serum supports the theory that Parry-Romberg syndrome may be an autoimmune disease, specifically a variant of localized scleroderma.

Parry-Romberg syndrome (also known as progressive hemifacial atrophy) is a rare neurocutaneous syndrome characterized by progressive shrinkage and degeneration of the tissues beneath the skin, usually on only one side of the face (hemifacial atrophy) but occasionally extending to other parts of the body.

PRS HFA progressive facial hemiatrophy progressive hemifacial atrophy Romberg syndrome None Parry-Romberg syndrome is a rare, acquired disorder characterized by slowly progressive shrinkage (atrophy) of the skin and soft tissues of half of the face (hemifacial atrophy).

Roughly 45% of people with Parry-Romberg syndrome are also afflicted with trigeminal neuralgia (severe pain in the tissues supplied by the ipsilateral trigeminal nerve, including the forehead, eye, cheek, nose, mouth and jaw) and/or migraine (severe headaches that may be accompanied by visual abnormalities, nausea and vomiting).

Parry-Romberg syndrome (also known as progressive hemifacial atrophy) is a rare neurocutaneous syndrome characterized by progressive shrinkage and degeneration of the tissues beneath the skin, usually on only one side of the face (hemifacial atrophy) but occasionally extending to other parts of the body.

PRS HFA progressive facial hemiatrophy progressive hemifacial atrophy Romberg syndrome None Parry-Romberg syndrome is a rare, acquired disorder characterized by slowly progressive shrinkage (atrophy) of the skin and soft tissues of half of the face (hemifacial atrophy).