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There may also be damage to the structures of the Papez circuit in this disease.
The mammillary bodies are an important part of the Papez circuit.
Recently, many studies have been done to analyze the anatomy and function of the Papez circuit.
An example of a memory circuit is the Papez circuit.
In the past few years, many experiments have been done that involve structures of the Papez circuit.
The Papez circuit involves various structures of the brain.
Moreover, many cases where structures of the Papez circuit have been damaged show changes that indicate its real function.
Consequently, many scientists believe that the Papez circuit is involved with memory because of theta wave experiments.
It is already known that problems with episodic memory are linked to tumors or damage in the Papez circuit.
The Papez circuit goes through the following neural pathway:
Degeneration or other neural problems because of this disease commonly occurs in parts of the Papez circuit.
This circuit referred to as the Papez circuit (1937) was said by its author to be the substrate for emotion.
Amnesia can be a result of disconnection of the mammillary bodies from the Papez circuit.
He theorized that these brain structures worked together as the emotional control center in the brain and consequently founded the Papez circuit.
Overall, based on theta wave experimentation, some components of the Papez circuit have shown to indeed have a connection and work together.
If there is damage, such as loss of neurons and/or myelination, to the mammillary bodies, the Papez circuit can be severely affected.
Damage to parts of the Papez circuit have shed light on not only its function, but on possible diagnosis of many disorders relating to memory.
Around the same time, Paul D. MacLean was also interested in the Papez circuit.
A photograph of the inferior medial view of the brain when dissected clearly shows the layout of the Papez circuit.
Damage to the hippocampus and other medial lobe structures in the Papez circuit is thought to be the cause of reduced or lost episodic memory.
This circuit, from amygdalae to mammillary bodies, and then on to the thalamus, is part of the larger Papez circuit.
The Papez circuit is a neural pathway in the brain first described by American neuroanatomist James Papez in 1937.
Various studies indicate that the Papez circuit is greatly influenced by the cerebellum and that perhaps the hippocampus is not the starting point of the circuit.
As a result of these adverse effects on episodic memory, damage to the Papez circuit can not only indicate or predict amnesia but also Alzheimer's in a patient.
The Papez circuit was later modified by American neuroscientist and physician Paul D. MacLean and now, the circuit is known as the limbic system.