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It lacks the ability to break down N-acetylglucosamine.
A study was done using N-acetylglucosamine 6-O-sulfotransferase-1 deficient mice.
Sanfilippo D is caused by the missing or deficient enzyme N-acetylglucosamine 6-sulfatase.
Phytohaemagglutinin has carbohydrate-binding specificity for a complex oligosaccharide containing galactose, N-acetylglucosamine, and mannose.
Chemically, chitin is a long-chain polymer of a N-acetylglucosamine, a derivative of glucose.
In the mammary gland, alpha-lactalbumin changes the substrate specificity of galactosyltransferase from N-acetylglucosamine to glucose.
MurNAc is a monosaccharide derivative of N-acetylglucosamine.
Commonly sold forms of glucosamine are glucosamine sulfate, glucosamine hydrochloride, and N-acetylglucosamine.
However, in the N-acetylglucosamine 6-O-sulfotransferase-1 deficient mice, the expression of keratan sulfate was significantly decreased when compared to the wild type mice.
Similarly, glial scar formation was significantly reduced in the N-acetylglucosamine 6-O-sulfotransferase-1 mice, and as a result, nerve regeneration was less inhibited.
The sugar component consists of alternating residues of β-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid.
The wild type mouse showed a significant up regulation of mRNA expressing N-acetylglucosamine 6-O-sulfotransferase-1 at the site of cortical injury.
All teicoplanins share a same glycopeptide core, termed teicoplanin A-1 - a fused ring structure to which two carbohydrates (mannose and N-acetylglucosamine) are attached.
Thsi mannan-binding lectin (MBL) recognizes patterns of neutral carbohydrates, such as mannose and N-acetylglucosamine.
Some Archaea have a similar layer of pseudopeptidoglycan or pseudomurein, where the sugar residues are β-(1,3) linked N-acetylglucosamine and N-acetyltalosaminuronic acid.
NOD1 and NOD2 recognize peptidoglycan motifs from bacterial cell which consists of N-acetylglucosamine and N-acetylmuramic acid.
Derivatives of amine containing sugars, such as N-acetylglucosamine and sialic acid, while not formally containing an amine, are also considered amino sugars.
Uridine diphosphate N-acetylglucosamine or UDP-GlcNAc is a nucleotide sugar and a coenzyme in metabolism.
MURNAc is covalently linked to N-acetylglucosamine and may also be linked through the hyroxyl on carbon number 4 to the carbon of L-alanine (Figure 9.26).
Microfungi are fungi, eukaryotic organisms such as molds, mildews and rusts, which exhibit tube tip-growth and have cell walls composed of chitin, a polymer of N-acetylglucosamine.
N-Acetylmuramic acid, or MurNAc, is the ether of lactic acid and N-acetylglucosamine with a chemical formula of CHNO.
The end-product of this pathway is Uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids.
Hyaluronic acid (or "hyaluronan") is a polysaccharide consisting of alternative residues of D-glucuronic acid and N-acetylglucosamine, and unlike other GAGs is not found as a proteoglycan.
Peptidoglycan consists of cross-linked amino acids and sugars which form alternating amino sugars: N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM).
These enzymes lengthen hyaluronan by repeatedly adding glucuronic acid and N-acetylglucosamine to the nascent polysaccharide as it is extruded via ABC-transporter through the cell membrane into the extracellular space.