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Within the cells, microtubule-organizing centers can take on many different forms.
Microtubules are often nucleated at a dedicated microtubule-organizing centre.
The first step in spindle formation is the nucleation of microtubules by microtubule-organizing centers, which then grow in all directions.
The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.
The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge.
Recruitment of γ-TuRC to the pericentrosomal region stabilizes microtubule minus-ends and anchors them near the microtubule-organizing center.
Microtubules are typically nucleated and organized by dedicated organelles called microtubule-organizing centres (MTOCs).
Microtubule-organizing centers function as the site where microtubule formation begin, as well as a location where free-ends of microtubules attract to.