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Researchers identified the maturation promoting factor that regulates cell division, and discovered the T-cell receptor which trigger responses of the immune system.
Cdk1 and cyclin B make up the maturation promoting factor (MPF) which promotes the entry into mitosis.
Dr. Masui discovered a protein known as M.P.F., for maturation promoting factor, that controls cell division in fertilized frog eggs.
The complex Cyclin B/cdc2 a.k.a. MPF (maturation promoting factor) promotes entry into mitosis.
The complex of Cdk and cyclin B is called maturation promoting factor or mitosis promoting factor (MPF).
Because the entry of oocytes into meiosis is frequently referred to as oocyte maturation, this cytoplasmic factor was called maturation promoting factor (MPF).
During G2 phase of the cell cycle, Cdk1 and Cyclin B1 makes a complex and forms Maturation promoting factor(MPF).
Biochemically, the end of G phase occurs when a threshold level of active cyclin B1/CDK1 complex, also known as Maturation promoting factor (MPF) has been reached.
The role of calcium in stimulating maturation promoting factor at fertilization was described earlier and here I shall concentrate on the G1 events that culminate in activation of DNA synthesis-promoting factor.
The CDKs associated with this checkpoint are activated by phosphorylation of the CDK by the action of a "Maturation promoting factor" (Mitosis Promoting Factor, MPF).