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The genetic techniques, he said, can produce mice with each form of the myelin basic protein.
Some, such as myelin basic protein, and spectrin have mainly structural roles.
Myelin basic protein has been shown to interact with Proteolipid protein 1.
Myelination is arrested at the promyelinating stage and in fish no myelin basic protein can be detected.
In fish this can be rescued by adding forskolin during development, which rescues myelin basic protein expression.
The material is similar to myelin basic protein, a natural component of the myelin sheath.
Levels of myelin basic protein were elevated in his cerebrospinal fluid, suggesting that demyelination was occurring.
(1992) Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy.
The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins.
Some of the proteins are myelin basic protein, myelin oligodendrocyte glycoprotein, and proteolipid protein.
The transcriptomes closely matched those of Schwann cells, revealing high activity in many of the genes coding for myelin basic protein production.
Given its resemblance to myelin basic protein, glatiramer may also act as a sort of decoy, diverting an autoimmune response against myelin.
In neurobiology, Hood was the first researcher to clone and study the myelin basic protein (MBP) gene.
The molecular mimicry hypothesis, in which T cells are essentially confusing HHV-6 with myelin basic protein, first appeared around this time.
Glatiramer acetate is a random polymer (average molecular mass 6.4 kD) composed of four amino acids that are found in myelin basic protein.
These activated T cells also recognized and initiated an immune response against a synthetically created peptide sequence that is identical to part of human myelin basic protein.
Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
Possible targets of the immune response include myelin basic protein (MBP) and proteolipid protein (PLP).
It also seems that myelin basic protein (MBP) from multiple sclerosis (MS) patients contains lower levels of phosphorylation at Thr97 than normal individuals.
The neuroimaging evidence can also be used to diagnose Grinker's myelinopathy through an elevation in the concentrations of a myelin basic protein in the cerebrospinal fluid .
Early on in the development of this hypothesis (2002), Italian researchers used the HHV-6a variant along with bovine myelin basic protein to generate cross-reactive T cell lines.
Dr Kies devoted energy and enthusiasm to the development of young scientists, and is known for her work on myelin basic protein and studies in animal models of multiple sclerosis.
Dirucotide is a synthetic peptide that consists of 17 amino acids linked in a sequence identical to that of a portion of human myelin basic protein (MBP).
It is a random polymer of four amino acids found in myelin basic protein, namely glutamic acid, lysine, alanine, and tyrosine, and may work as a decoy for the immune system.
Multiple sclerosis - phosphorylation pathways Myelin basic protein (MBP) regularly exchanges phosphate groups with the environment, and its ability to do so has implications for proper myelin sheath integrity.