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The old name, Letterer-Siwe Disease, stands for Erich Letterer and Sture Siwe.
Multifocal multisystem LCH, also called Letterer-Siwe disease, is a rapidly-progressing disease in which Langerhans cells proliferate in many tissues.
Vinblastine is used to treat Hodgkin's disease, certain types of lymphoma, testicular cancer, breast cancer, choriocarcinoma (a type of uterine cancer), Kaposi's sarcoma, and Letterer-Siwe disease.
Types of LCH have also been known as "Eosinophilic Granuloma", "Hand-Schuller-Christian Disease", "Letterer-Siwe Disease", and "Histiocytosis X".
Histiocytosis-X Eosinophilic Granuloma Hand-Schuller Christian Syndrome Letterer-Siwe Disease None Langerhans cell histiocytosis (LCH) is a non-malignant proliferation of Langerhans cells (LC).