hyperimmunoglobulin E syndrome
hyper-IgE syndrome , HIES (Abkürzung)
Job syndrome

Hyperimmunoglobulin E syndrome, an immune disorder characterized by high levels of serum IgE.

Hyperimmunoglobulin E syndrome (also known as Job's Syndrome)

Loss-of-function mutations in the STAT3 gene result in Hyperimmunoglobulin E syndrome, associated with recurrent infections as well as disordered bone and tooth development.

Hyperimmunoglobulin E syndrome (HIES), also called Job's syndrome and Buckley syndrome, is a heterogeneous group of immune disorders.

A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

This variant of Hyperimmunoglobulin E syndrome (HIES) was first described in 2004 and was now found to have a genetic mutation in the DOCK8 gene.

Atopic individuals can have up to 10 times the normal level of IgE in their blood (as do sufferers of hyper-IgE syndrome).

It's the old JOB syndrome all over again.

AR-HIES HIES hyperimmunoglobulin E recurrent infection syndrome Job syndrome, autosomal recessive HIE syndrome None Autosomal recessive hyper IgE syndrome (AR-HIES) is a rare primary immunodeficiency disorder.