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Granule neurons also extend out to make contacts with Golgi cells.
"Changes in the Golgi cells?"
Mossy fibers and golgi cells both make synaptic connections with granule cells.
In neuroscience, Golgi cells are inhibitory interneurons found within the granular layer of the cerebellum.
The Golgi cell acts by altering the mossy fibre - granule cell synapse.
Terminals from Golgi cells infiltrate the structure and make inhibitory synapses onto the granule cell dendrites.
The Golgi cells use GABA as their transmitter.
These enlargements are sites of excitatory input from mossy fibers and inhibitory input from Golgi cells.
Golgi cells provide inhibitory feedback to granule cells, forming a synapse with them and projecting an axon into the molecular layer.
In the rat cerebellum, the protein has also been found in the Golgi cells of the granular layer, and in the Purkinje cells.
At the bottom lies the thick granular layer, densely packed with granule cells, along with interneurons, mainly Golgi cells but also including Lugaro cells and unipolar brush cells.
The innermost layer contains the cell bodies of three types of cells: the numerous and tiny granule cells, the slightly larger unipolar brush cells and the much larger Golgi cells.
A few neuronal cell types are not recognized by the NeuN antibody, such as cerebellar Purkinje cells and Golgi cells, olfactory Mitral cells and retinal photoreceptors.
Consistently, in the cerebellum, Golgi cells express c-fos mRNA to CCK8 injection, whereas granule cells express junD mRNA to capsaicin injection to the limb skin.
Granule cells are also subject to feedback inhibition: Golgi cells receive excitatory stimulus from granule cells and in turn the golgi cells send back inhibitory signals to the granule cell.