One such alteration is decreased affinity for Cyclic guanosine monophosphate.

Guanosine monophosphate is produced from dried fish or dried seaweed.

It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase.

Sensitivity to light is modulated by changes in intracellular calcium ions and cyclic guanosine monophosphate.

Cyclic guanosine monophosphate (cGMP) plays an important role in visual transductions.

It exerts its effects by binding to cytosolic guanylate cyclase and stimulating the production of cyclic guanosine monophosphate.

Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells.

As inhibitor of guanosine monophosphate synthesis in experimental models, the glutamine analogue DON can be used.

Sutherland continued to be involved in novel research about adenosine monophosphate and guanosine monophosphate co-authoring four papers in 1973 alone.

For example, they convert adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine.

Cyclic guanosine monophosphate (cGMP)

It is caused by a defect in the gene for cGMP-phosphodiesterase, which leads to retinal levels of cyclic guanosine monophosphate ten times normal.

As well it hinders guanylyl cyclase and therefore the forming of cyclic guanosine monophosphate (cGMP).

Nesiritide works to facilitate cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldoesterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation.

HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate.

This compound is a potent inhibitor of cGMP specific phosphodiesterase type 5, the enzyme that degrades the signalling molecule cyclic guanosine monophosphate.

Among all of the computationally screened compounds, pentamidine, 1,3-dinitroadamantane, acyclovir and analogs of acyclovir had higher binding affinities than the real substrate (guanosine monophosphate).

Hydralazine increases cyclic guanosine monophosphate (cGMP) levels, increasing the activity of protein kinase G (PKG).

The degradation of guanosine monophosphate yields xanthine as an intermediate product which is then converted in the same way to uric acid with the formation of hydrogen peroxide.

In his early reseach years, Dr. Murad worked on a chemical known as cyclic guanosine monophosphate, which later turned out to be critical in the nitric oxide story.

Cyclic guanosine monophosphate (cGMP) is a cyclic nucleotide derived from guanosine triphosphate (GTP).

The activation of soluble guanylate cyclase by NO to produce the second messenger cyclic guanosine monophosphate (cGMP) is inhibited by methylene blue.

Guanylyl transferases are enzymes that transfer a guanosine monophosphate (GMP; also known as guanylic acid) group, usually from GTP to another molecule, releasing pyrophosphate.

The former is an indicator of quality materials and good manufacturing processes.

She said the agency had held up the imports because of issues related to compliance with F.D.A. requirements called good manufacturing processes.

The manufacturer, Centeon, a subsidiary of Rhone-Poulenc, in King of Prussia, Pa., stopped production voluntarily from January to September after drug agency inspectors found "very serious breaches of good manufacturing process," Dr. Epstein said.

Although the FDA issued a final rule establishing regulations to require manufacturers of dietary supplements to prove good manufacturing processes and to correctly label their ingredients,[56] the standardization of products such as St. John's wort with respect to the desired amount of potentially active ingredients is not carried out.