Inside a cancer cell, the virus is able to replicate, secreting GM-CSF in the process.

The GM-CSF attracts dendritic cells to the site.

The day before he left, he had heard a report by a doctor from Mainz on the medical use of GM-CSF.

Studies have shown GM-CSF can accelerate the process and can increase the survival rate of patients whose transplants fail.

It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF.

"It not only gets them out first, it establishes GM-CSF as the first colony-stimulating factor on the market," he said.

The virus kills them by lysis and also expresses GM-CSF which may help initiate an anti-tumour immune response.

It is based on an engineered version of herpes simplex virus which has also been engineered to express GM-CSF.

Systemic GM-CSF was detected up to 7 weeks following both intratumoral and intravenous injection of JX-594.

Secrete the cytokine GM-CSF (a protein naturally secreted in the body to initiate an immune response)

TNFα and recombinant GM-CSF independently promote IL-10 production in U937 cells.

Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma.

The MVA expresses the HIV virus-like-particles, but does not express GM-CSF.

It is a second-generation herpes simplex virus based on the JS1 strain and expressing the immune stimulatory factor GM-CSF.

The stock tumbled again after Shearson Lehman Brothers issued a scathing report on April 22 about prospects for the company's next major drug, called GM-CSF.

Amgen Inc. markets a drug called G-CSF, which has been enormously successful, and Immunex markets GM-CSF.

Karthik Nagesh N.The Indian Multicenter randomized trial with GM-CSF in Neonatal sepsis.

Principal Investigator, The "first Indian Multicenter Research Trial" on determining the role of GM-CSF in Neonatal Sepsis.

The novel vaccine consists of a recombinant DNA vaccine co-expressing human GM-CSF and non-infectious HIV virus-likeparticles.

Talimogene laherparepvec is the USAN name for the oncolytic virus also known as 'OncoVEX GM-CSF'.

In 2005, encouraging but mixed results of vaccination were reported with the BCR/abl p210 fusion protein in patients with stable disease, with GM-CSF as an adjuvant.

The immunostimulatory cytokine GM-CSF is produced from the JX-594 genome following infection, inducing immune response against both the virus and the tumor and enabling lasting tumor immunity.

This can be further enhanced by priming with a mixture of plasmids encoding PyCSP and murine GM-CSF, before boosting with recombinant vaccinia virus.

Simons' laboratories at Johns Hopkins University and Emory University made original contributions to prostate cancer immunotherapy after inventing GM-CSF genetically engineered vaccines for prostate cancer.

GM-CSF is found in high levels in joints with rheumatoid arthritis and blocking GM-CSF may reduce the inflammation or damage.