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Whether the glucose transporter plays any role in these cells remains to be shown.
The function of these new glucose transporter isoforms is still not clearly defined at present.
More specifically, there are glucose transporters located in the brain cells (neurons).
Whenever women lose their estrogen supply at menopause, there's less or a slower development of glucose transporters.
GLUT1 was the first glucose transporter to be characterized.
Structure, function, and regulation of the mammalian facilitative glucose transporter gene family.
Dematin- interaction with the Glut1 glucose transporter.
Later, it was found that Snf3 is not a glucose transporter, but rather a high affinity glucose sensor.
It is actively imported into the endoplasmic reticulum of cells via glucose transporters.
Based on this homology and on genetic studies, Snf3 was initially thought to be a high affinity glucose transporter.
Glucose is then exported from the cell via glucose transporter membrane proteins.
There are over 10 different types of glucose transporters; however, the most significant for study are GLUT1-4.
Snf3 is a plasma membrane protein in yeasts that consists of 12 (2x6) transmembrane domains, like the homologous glucose transporters.
Mutations in the SLCA21 gene can cause the glucose transporter to decrease in function or stop completely.
Indeed, while hepatocytes and myocytes have mechanisms allowing them to internalize their glucose transporter, endothelial cells do not possess this ability.
It does this by decreasing the translocation of glucose transporters (especially GLUT4) to the cell membrane.
Glucose is shuttled into the cytoplasm by glucose transporters located in the endoplasmic reticulum's membrane.
All glucose transporters including Snf3 contain an arginine residue situated in a cytoplasmic loop preceding the fifth transmembrane domain.
Akt2 is required for the insulin-induced translocation of glucose transporter 4 (GLUT4) to the plasma membrane.
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose over a plasma membrane.
Specifically, it leads to upregulation of glucose transporters in the cell membrane in order to increase glucose uptake from the bloodstream.
GLUT8 also known as SLC2A8 is the eighth member of glucose transporter superfamily.
The inability of cells expressing sgrS to create new glucose transporters leads to less glucose uptake and reduced levels of glucose-6-phosphate.
It has been proposed that SgrT exerts its effects through regulation of the glucose transporter, PtsG.
Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes.