Fanconi anaemia , auch: Fanconi's anemia

Sarah is later diagnosed with a blood disorder, Fanconi Anaemia.

In late 2011, Andy and Debbie's daughter Sarah becomes ill and she is then diagnosed with Fanconi anaemia, a genetic disorder which could kill her without treatment.

However, chromosomal instability syndromes such as Bloom's syndrome, ataxia telangiectasia and Fanconi anaemia are inherited and are considered to be genetic diseases.

Jamie is having problems finding a donor to save him from a condition known as Fanconi anaemia because in Malta we do not currently have a register of bone marrow donors.

Fanconi Anaemia: Fanconi Anaemia is a disorder that predisposes patients to cancer due to its effect on DNA repair pathways.

Examples of autosomal recessive cancer syndromes are; ataxia telangiectasia, Bloom syndrome, Fanconi anaemia, Rothmund-Thompson syndrome, Werner's syndrome and Xeroderma pigmentosum.

As well as this, poor clinical outcome in neuroblastomas (such as those caused by deletion of the FANC gene in Fanconi Anaemia) has been linked to the frequent occurrence chromothripsis.

Campbell served a short stint as a director of publicly listed not-for-profit organisation, Fanconi Anaemia Australia Limited before resigning to run as a candidate in the Adelaide City Council election in 2007.

The HLA matching can be combined with the diagnosis for monogenic diseases such as Fanconi anaemia or b-thalassemia in those cases where the ailing sibling is affected with this disease, or it may be exceptionally performed on its own for cases such as children with leukaemia.

Fanconi anaemia Predisposition of acute myeloid leukemia; skeletal abnormalities; radial hypoplasia and vertebral defect and other physical abnormalities, bone marrow failure (pancytopenia), endocrine dysfunction, early onset osteopenia/osteoporosis and lipid abnormalities, spontaneous chromosomal breakage exacerbated by exposure to DNA cross-linking agents.